The Dhr38 gene codes for a protein belonging to superfamily of steroid hormone receptors and plays an important role in regulation of metamorphosis processes at late developmental stages in D. melanogaster
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چکیده
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Drosophila hormone receptor 38 functions in metamorphosis: a role in adult cuticle formation.
DHR38 is a member of the steroid receptor superfamily in Drosophila homologous to the vertebrate NGFI-B-type orphan receptors. In addition to binding to specific response elements as a monomer, DHR38 interacts with the USP component of the ecdysone receptor complex in vitro, in yeast and in a cell line, suggesting that DHR38 might modulate ecdysone-triggered signals in the fly. We characterized...
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